TITLE:
Sulfuric Acid Immobilized on Silica Gel as Highly Efficient and Heterogeneous Catalyst for the One-Pot Synthesis of 2,4,5-Triaryl-1H-imidazoles
AUTHORS:
Behrooz Maleki, Hossein Keshvari Shirvan, Fereshteh Taimazi, Elahe Akbarzadeh
KEYWORDS:
2, 4, 5-Trisubstituted Imidazoles; Solvent-Free Synthesis; Multicomponent Reaction; Silica-Supported Sulfuric Acid; Heterogeneous Catalyst
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.2 No.1,
March
15,
2012
ABSTRACT: Application of sulfuric acid immobilized on silica gel as an efficient and benign catalyst has been explored in the syn-thesis of 2,4,5-Triaryl-1H-imidazoles via condensation reaction of benzil or benzoin, aldehyde and ammonium acetate. The key advantages of this process are high yields, cost effectiveness of catalyst, easy work-up, purification of products by non-chromatographic method and the reusability of the H2SO4.SiO2 catalyst.