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Zhong, J.X., Lin, X.R. and Hu, H. (2022) Research Progress on Regulating Exhausted CD8+ T Cells by Metabolic Reprogramming of Tumor Microenvironment. Biomedical Translation, 3, 46-56.

has been cited by the following article:

• TITLE: Advances in the Mechanism of Action of Gamma-Glutamyltransferase and Lactate Dehydrogenase in Colorectal Cancer

  AUTHORS: Yuxiang Zhang, Yana Wei

  KEYWORDS: Colorectal Cancer, Gamma-Glutamyltransferase, Lactate Dehydrogenase, Mechanism of Action

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.13 No.8, August 1, 2025

  ABSTRACT: As the third most common malignant tumor in the world, colorectal cancer (CRC) poses a serious threat to human life and health with its high morbidity and mortality. Although early-stage patients can realize the possibility of cure through surgery, advanced-stage patients have a poor prognosis. Research has found that gamma-glutamyl transferase (GGT) and lactate dehydrogenase (LDH) are associated with the occurrence, development, and prognosis of colorectal cancer. Therefore, exploring their roles in the occurrence and development of colorectal malignancies can help identify new therapeutic targets for cancer treatment. This article reviews the relevant mechanisms of GGT and LDH in colorectal cancer.