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Kesic, V., Carcopino, X., Preti, M., Vieira-Baptista, P., Bevilacqua, F., Bornstein, J., et al. (2023) The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) Consensus Statement on the Management of Vaginal Intraepithelial Neoplasia. International Journal of Gynecological Cancer, 33, 446-461.
https://doi.org/10.1136/ijgc-2022-004213
has been cited by the following article:
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TITLE:
Follow-Up of HPV Clearance after LEEP Conization and Vaporization for CIN2+, and Vaporization for VaIN2
AUTHORS:
Kenji Niwa, Saki Tsurue, Rui Kyogoku, Masanori Isobe, Yoh Hayasaki, Sakae Mori, Keigo Kuwabara, Kentaro Niwa, Takuji Tanaka
KEYWORDS:
HPV, CINs, LEEP Conization, Vaporization, VaIN
JOURNAL NAME:
Open Journal of Pathology,
Vol.15 No.3,
July
8,
2025
ABSTRACT: LEEP conization with vaporization was performed for 86 CIN2+ cases. Our data suggest that combining LEEP conization and vaporization results in a higher estimated cumulative HPV clearance rate than LEEP alone. The clearance rate tended to be better in younger patients. Vaporization could provide a promising therapeutic option for VaIN2 associated with high-risk HPV infection. Treatment of CIN2+ and VaIN2 using ball electrode vaporization and LEEP conization appears feasible and effective, even in settings lacking specialized surgical devices. After conservative treatment of CINs or VaIN, HR-HPV persists in some cases even in the NILM state without dysplasia, and long-term follow-up is needed.