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J. Ohtsubo and T. Asakura, “Velocity Measurement of a Diffuse Object by Using Time-Varying Speckles,” Optical and Quantum Electronics, Vol. 8, No. 6, 1976, pp. 523-529. doi:10.1007/BF00620143

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• TITLE: A Hybrid De-Noising Method on LASCA Images of Blood Vessels

  AUTHORS: Cong Wu, Nengyun Feng, Koichi Harada, Pengcheng Li

  KEYWORDS: Brain Blood Flow; Wavelet Fusion; Hybrid Filtering; Laser Speckle Contrast Imaging

  JOURNAL NAME: Journal of Signal and Information Processing, Vol.3 No.1, February 29, 2012

  ABSTRACT: A de-noising approach is proposed that based on the combination of wiener filtering, nonlinear filtering and wavelet fusion, which de-noise the LASCA (LAser Speckle Contrast Analysis) image of blood vessels in Small Animals. The approach first performs laser spectral contrast analysis on brain blood flow in rats, get their spatial and temporal contrast images. Then, a de-noising filtering method is proposed to deal with noise in LASCA. The image restoration is achieved by applying the proposed admixture filtering, and the subjective estimation and objective estimation are given to the de-noising images. As our experimental results shown, the proposed method provides clearer subjective sense and improved to over 25 db for PSNR.