TITLE:
A Progressive Desmoid Tumor of the Shoulder Girdle: Case Report and Literature Review
AUTHORS:
Carlos Hernández Brito, Pedro Arredondo Ruiz, Omar Josué Herrera López, Luis Ángel Amezcua Toledo, Brenda Paola Sáenz Dávila, Itzel Reyes De La Garza, Luis Eduardo Méndez Turrubiates, Arsenio Torres Delgado, Yara Grisel Flores Raymundo
KEYWORDS:
Desmoid Tumor, Desmoid-Type Fibromatosis, Aggressive Fibromatosis, Deep Fibromatosis, Musculoaponeurotic Fibromatosis, Shoulder Girdle
JOURNAL NAME:
Surgical Science,
Vol.16 No.5,
May
23,
2025
ABSTRACT: Background: Desmoid tumor (DT) is a rare locally aggressive tumor of unpredictable evolution that develops in deep soft tissues with an infiltrative growth pattern and with a high tendency to local recurrence. Only 17% of extra-abdominal DT develops in the shoulder girdle. Aim: Describe the behavior and unpredictable evolution of DT as well as the different treatment options currently recommended, along with their advantages and disadvantages. Case Presentation: A 29-year-old female with a DT in the shoulder girdle of 6 years of evolution with progressive growth, pain, and limitation in the joint movements treated with chemotherapy presenting stable disease and switching to Tyrosine Kinase Inhibitors (TKI) with progressive disease for which a R0 resection was performed. Currently, under surveillance with a 3-year disease-free survival and a control computed tomography (CT) scan with no data of tumor activity. Conclusion: DT treatment should be multidisciplinary and individualized based on the behavior, location, and size of the tumor, the functional status of the limb, secondary symptoms, the risk of complications if the disease continues to progress, and the patient’s decision.