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Raju, G.S.R., Pavitra, E., Bandaru, S.S., Varaprasad, G.L., Nagaraju, G.P., Malla, R.R., et al. (2023) HOTAIR: A Potential Metastatic, Drug-Resistant and Prognostic Regulator of Breast Cancer. Molecular Cancer, 22, Article No. 65.
https://doi.org/10.1186/s12943-023-01765-3

has been cited by the following article:

• TITLE: The Predictive Role of LncRNA Molecules (HOTAIR) in Breast Cancer Prognosis

  AUTHORS: Faisal Redwan, Nader Abdullaa, Eyad Alshatti, Ansam Abdullah

  KEYWORDS: Breast Cancer, HOTAIR, Tumor Grade, HER2 Receptor, HR Receptors

  JOURNAL NAME: Open Access Library Journal, Vol.12 No.4, April 8, 2025

  ABSTRACT: Objective: The aim of the present study is to assess the role of the level of change in gene expression of the HOTAIR molecule in breast cancer patients. Methods: An assay was conducted for the level of gene expression of the HOTAIR molecule in the plasma of 30 patients and 10 healthy controls, by performing the reverse transcription reaction RT-qPCR, gene expression was evaluated using the Livak equation, tumor characteristics (grade, HER2 receptors, hormonal (HR) receptors) were also studied in the Pathological Anatomy Department and compared between patients. Results: The results of the study showed that there was a significant difference (P Conclusion: It was found that the gene expression level of HOTAIR molecule may have a prognostic significance in the diagnosis of breast cancer and the characteristics of the tumor responsible for increasing tumor virulence and poor prognosis.