TITLE:
Proposal of a New Therapeutic Approach for Adult Atypical Teratoid/Rhabdoid Tumor Based on Literature Review and Case Report
AUTHORS:
Nathan Gaquere, Maxime Rivollier, Philippe Colin, Claude-Fabien Litré, Jean-Charles Kleiber
KEYWORDS:
Adult, Atypical Teratoid/Rhabdoid Tumor, Brain, Childhood Tumor, Survival
JOURNAL NAME:
Voice of the Publisher,
Vol.11 No.1,
March
24,
2025
ABSTRACT: Rhabdoid tumors are aggressive soft tissue sarcomas predominantly affecting children under three years of age. While rare, cases of Atypical Teratoid/Rhabdoid Tumors (AT/RT) have been reported in adults, presenting unique challenges for treatment. This article presents a new therapeutic approach for adult AT/RT based on a case report and literature review. The case involves an adult male diagnosed with AT/RT who achieved a ten-year survival through a comprehensive treatment regimen. The approach includes surgical resection, intensive chemotherapy, and radiation therapy. The study highlights the importance of adopting an intensive chemotherapy protocol, typically used in pediatric cases, as a promising strategy for adult AT/RT management. This innovative proposal underscores the need for further research and therapeutic advancements to improve outcomes in this rare disease.