TITLE:
The Role of Microglia in Pediatric Neurological Disorders
AUTHORS:
Harmehar Kaur
KEYWORDS:
Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment
JOURNAL NAME:
Neuroscience and Medicine,
Vol.16 No.1,
March
13,
2025
ABSTRACT: Microglia, the central nervous system’s resident immune cells, play a pivotal role in brain development and function, particularly in pediatric neurological disorders. This review explores the molecular mechanisms underlying microglial dysfunction in conditions such as autism spectrum disorder, epilepsy, and juvenile neurodegenerative diseases, emphasizing their age-dependent roles. Therapeutic strategies targeting microglial activity are discussed, highlighting the need for precise, age-appropriate interventions to mitigate neurodevelopmental deficits and improve outcomes for affected children.