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Shirwaikar Annie, Rajendran, K. and Rakesh, B. (2006) Effect of aqueous bark extracts of Garuga pinnata in streptozotocin-nicotinamide induced type-II diabetes mellitus. Journal of Ethnopharmacology, 107, 285-290. doi:10.1016/j.jep.2006.03.012

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• TITLE: Comparative study between the effect of Momordica charantia (wild and hybrid variety) on hypoglycemic and hypolipidemic activity of alloxan induced type 2 diabetic long-evans rats

  AUTHORS: Subbroto Kumar Saha, Md. Ezazul Haque, Dipa Islam, Md. Matiar Rahman, Md. Rezuanul Islam, Anzana Parvin, Shahedur Rahman

  KEYWORDS: Type 2 Diabetes Mellitus; Momordica Charantia; Alloxan, Hypoglycemic Effect; Hypolipidemic Effect; Glibenclamide

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.2 No.1, February 22, 2012

  ABSTRACT: This study was undertaken to evaluate the hypoglycemic and hypolipidemic effect of Momordica charantia (wild and hybrid variety) powder on alloxan induced type 2 diabetic male Long-Evans rats. Oral feeding of the M. charantia powder slightly decreased serum total cholesterol, triglyceride levels and LDL-cholesterol compared with wild, hybrid and standard drug. M. charantia wild variety showed more significant (p M. charantia did not show any significant effect on HDL-cholesterol and liver glycogen. Thus, results of the study prove that the wild variety of M. charantia fruit have potent antidiabetic and antilipidemic property.