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Grover, J.K., Vats, V. and Rathi, S.S. (2000) Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. Journal of Ethnopharmacology, 73, 461-470. doi:10.1016/S0378-8741(00)00319-6

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• TITLE: Comparative study between the effect of Momordica charantia (wild and hybrid variety) on hypoglycemic and hypolipidemic activity of alloxan induced type 2 diabetic long-evans rats

  AUTHORS: Subbroto Kumar Saha, Md. Ezazul Haque, Dipa Islam, Md. Matiar Rahman, Md. Rezuanul Islam, Anzana Parvin, Shahedur Rahman

  KEYWORDS: Type 2 Diabetes Mellitus; Momordica Charantia; Alloxan, Hypoglycemic Effect; Hypolipidemic Effect; Glibenclamide

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.2 No.1, February 22, 2012

  ABSTRACT: This study was undertaken to evaluate the hypoglycemic and hypolipidemic effect of Momordica charantia (wild and hybrid variety) powder on alloxan induced type 2 diabetic male Long-Evans rats. Oral feeding of the M. charantia powder slightly decreased serum total cholesterol, triglyceride levels and LDL-cholesterol compared with wild, hybrid and standard drug. M. charantia wild variety showed more significant (p M. charantia did not show any significant effect on HDL-cholesterol and liver glycogen. Thus, results of the study prove that the wild variety of M. charantia fruit have potent antidiabetic and antilipidemic property.