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Barova, H., Perusicova, J., Hill, M., Sterzl, I., Vondra, K. and Masek, Z. (2004) Anti-GAD-positive patients with type 1 diabetes mellitus have higher prevalence of autoimmune thyroiditis than anti-GAD-negative patients with type 1 and type 2 diabetes mellitus. Physiological Research, 53, 279-286.
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TITLE:
Reduced endogenous insulin secretion in diabetic patients with low-titer positive antibodies against GAD
AUTHORS:
Yuichiro Takeuchi, Hiroyuki Ito, Koshiro Oshikiri, Shinichi Antoku, Mariko Abe, Mizuo Mifune, Michiko Togane, Masahiro Kato
KEYWORDS:
GAD Antibody; Endogenous Insulin Secretion; Urinary C-Peptide; SPIDDM; LADA
JOURNAL NAME:
Journal of Diabetes Mellitus,
Vol.2 No.1,
February
22,
2012
ABSTRACT: Aim: To investigate the clinical characteristics of diabetic patients with a low-titer positive for the anti-glutamic acid decarboxylase 65 antibody (GAD antibody). Methods: The subjects were 420 diabetic inpatients. The endogenous insulin secretion was estimated on the basis of the C-peptide immunoreactivity from a 24 h urine collection (uCPR). Clinical variables were compared between patients negative for the GAD antibody (GAD antibody titer