TITLE:
Adolescent-Onset Triple-Antibody Positive Juvenile Dermatomyositis Found in Hispanic Male Wrestler: A Case Report and Literature Review
AUTHORS:
Rajvee Sanghavi, Patrycja Tesmer, Deepika Singh, Sukesh Sukumaran
KEYWORDS:
Juvenile Dermatomyositis, Myositis-Associated Antibodies, Myositis-Specific Antibodies
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.15 No.1,
February
28,
2025
ABSTRACT: In this manuscript, we present a case report of a child with 16-year-old previously healthy Hispanic male who presented for progressive proximal muscle weakness, rash, and dysphagia. He was admitted to the acute care floor and diagnosed with juvenile dermatomyositis and found to be positive for anti-Mi-2 alpha, anti-Mi-2 beta, and anti-MDA-5 antibodies. He gradually improved with a combination of steroid, immunomodulatory treatment, and physical therapy. This case outlines the clinical course of a patient with this rare disorder as well as the importance of understanding the role of associated antibodies to manage potential long-term sequelae.