TITLE:
Association between Vascular Calcification and Bone Mineral Density in Chronic Hemodialysis Patients: A Single Moroccan Center Experience
AUTHORS:
Majdouline Errihani, Kawtar Hassani, Aya Sobhi, Sanaa Benbria, Yassir Zajjari, Driss Elkabbaj
KEYWORDS:
Bone Mineral Density, Hemodialysis, Vascular Calcification
JOURNAL NAME:
Open Access Library Journal,
Vol.12 No.1,
January
31,
2025
ABSTRACT: Introduction: Chronic kidney disease-mineral and bone disorders (CKD-MBD) are characterized by generalized vascular calcification (VC) and impaired bone health. We aimed to investigate the relationship between VC and bone mineral density (BMD) in chronic hemodialysis patients. Methods: A cross-sectional study included 40 chronic hemodialysis patients for at least 6 months. For the assessment of VC, abdominal aorta lateral lumbar X-rays were used, and for the analysis of bone mineral density, dual-energy X-ray absorptiometry (DXA) at the lumbar spine (LS) and femoral neck (FN) was provided. Results: Forty patients were included; the average age was 59 ± 16 years, 47% were women, and the median of hemodialysis duration was 54 months. The prevalence of AAC was 57.5%; and the median AAC score was 3 [0.10]. The prevalence of osteoporosis at the lumbar spine was 27.5%, while at the femoral neck, it was 32.5%. The mean BMD at the lumbar spine was 0.999 ± 0.213; and at the femoral neck, it was 0.814 ± 0.239. In the correlation analysis, there was a significant association between AAC and BMD; ACC was inversely correlated with BMD of the spine (r = −0.368, p = 0.019) and femoral neck (r = −0.578, p Conclusion: Our study demonstrated that the presence of CV reduces BMD in hemodialysis patients; this implies the need for early diagnosis and optimal management of CKD-MBD. We believe that the results of our study will help in the planning of future research, as they also confirm the existence of the vascular-bone axis.