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J. M. Holly and C. M. Perks, “Cancer as an Endocrine Problem,” Best Practice and Research Clinical Endocrinology and Metabolism, Vol. 22, No. 4, 2008, pp. 539-550. doi:10.1016/j.beem.2008.07.007

has been cited by the following article:

• TITLE: Quantification of Steroid Receptors Gene Expression in Breast Cancer Patients: Possible Correlation with Serum Level of Adipocytokines

  AUTHORS: Rana Jahanban Esfahlan, Nosratollah Zarghami, Μohammad Rahmati-Yamchi, Amir Monfaredan, Samira Valiyari, Ali Jahanban Esfahlan, Raziallah Jafari Jozani, Morteza Gojazadeh, Fereidoun Mamaghani, Majid Mobasseri

  KEYWORDS: Obesity, Breast Cancer, Steroid Receptors, Adipocytokines

  JOURNAL NAME: Journal of Cancer Therapy, Vol.2 No.5, December 31, 2011

  ABSTRACT: Background: While the role of adipocyte-derived hormones in breast cancer pathogenesis well studied, it is speculated that there is a crosstalk between adipocytokines and Esterogen receptor(ER) signaling. To test this hypothesis we evaluate the possible correlation between serum levels of adipocytokins with steroid hormone receptors gene expression in breast cancer patients. Methods: In this case-control study, 70 women with breast cancer participated with different grades of obesity (36 none obese, BMI 0.05). In case of leptin, we observed a positive correlation between leptin and ERα and PR mRNA. (r = 0.553, n = 64, p