TITLE:
Thiosemicarbazone (E)-2(1-(2-Hydroxyphenyl) Hydrazine)-1-Carbothioamide: Spectroscopic Studies, Xray Diffractometer Characterization and Antioxydant Test
AUTHORS:
Bogou Ndiaye, Thierno Moussa Seck, Aîssatou Aliou Gaye, Blaise Kama, Waly Diallo, Cheikh Abdoul Khadir Diop, Erwann Jeanneau
KEYWORDS:
Semicarbazone, Monoclinic, Spectroscopic, Antioxydant Tests
JOURNAL NAME:
Journal of Materials Science and Chemical Engineering,
Vol.12 No.12,
December
31,
2024
ABSTRACT: In the present work, a new semithiocarbazone ligand C3NH4CONHNC(CH3) C6H4OH H4L2 have been isolated and characterized by single-crystal X-ray diffraction. Compound H4L2 crystallizes in the monoclinic system space group P21/n with a = 10.9328(9), b = 8.1700(6), c = 13.8095(11) Å, β = 93.7591(14)˚, V = 3671.57(9) Å3, Z = 16, Z’ = 2. Semithiocarbazone connected through NH···O and OH···O hydrogen bonds. In the crystal, the structure is organized in layer-like arrangements. Structural characterizations were completed by infrared and 1H, 13C{1H} spectroscopy and elemental analysis which corroborate the X-ray elucidations. In another case, this organic compound is submitted to antioxidant test. The test has been done by using Akhtar et al. methods [1] with some modifications. The tests are done with different concentration of solutions between 100 to 500 μM. The values of per cent of inhibition (5.18% - 25.90%) of the solution containing semithiocarbazone organic compound show a real difference compared to the values of the reference TROLOX. These results show that our organic ligand C3NH4CONHNC(CH3)C6H4OH is a good antioxidant compound.