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Inzucchi, S.E., Zinman, B., Fitchett, D., Wanner, C., Ferrannini, E., Schumacher, M., et al. (2017) How Does Empagliflozin Reduce Cardiovascular Mortality? Insights from a Mediation Analysis of the EMPA-REG OUTCOME Trial. Diabetes Care, 41, 356-363.
https://doi.org/10.2337/dc17-1096

has been cited by the following article:

• TITLE: SGLT-2 Inhibitors: The Magic Bullet for Cardio-Renal Protection in Type 2 DM

  AUTHORS: Rushi Patel, Terry Oroszi

  KEYWORDS: SGLT-2 Inhibitors, Type 2 Diabetes Mellitus, Cardiovascular Outcomes, Renal Protection, Glycemic Control

  JOURNAL NAME: Pharmacology & Pharmacy, Vol.15 No.12, December 30, 2024

  ABSTRACT: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a promising class of medications for type 2 diabetes mellitus (DM2) treatment. This study aims to evaluate the clinical efficacy, safety, and potential benefits of SGLT-2 inhibitors in improving cardiovascular and renal outcomes in DM2 patients. A comprehensive review of clinical trials and studies on SGLT-2 inhibitors was conducted. SGLT-2 inhibitors significantly improve glycemic control, reduce cardiovascular mortality, and lower the risk of renal events in DM2 patients. SGLT-2 inhibitors offer substantial cardio-renal protection in DM2 management, though further research is needed to optimize their use.