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Sun, X., Han, F., Lu, Q., Li, X., Ren, D., Zhang, J., et al. (2020) Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice. Diabetes, 69, 1292-1305.
https://doi.org/10.2337/db19-0991

has been cited by the following article:

• TITLE: SGLT-2 Inhibitors: The Magic Bullet for Cardio-Renal Protection in Type 2 DM

  AUTHORS: Rushi Patel, Terry Oroszi

  KEYWORDS: SGLT-2 Inhibitors, Type 2 Diabetes Mellitus, Cardiovascular Outcomes, Renal Protection, Glycemic Control

  JOURNAL NAME: Pharmacology & Pharmacy, Vol.15 No.12, December 30, 2024

  ABSTRACT: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a promising class of medications for type 2 diabetes mellitus (DM2) treatment. This study aims to evaluate the clinical efficacy, safety, and potential benefits of SGLT-2 inhibitors in improving cardiovascular and renal outcomes in DM2 patients. A comprehensive review of clinical trials and studies on SGLT-2 inhibitors was conducted. SGLT-2 inhibitors significantly improve glycemic control, reduce cardiovascular mortality, and lower the risk of renal events in DM2 patients. SGLT-2 inhibitors offer substantial cardio-renal protection in DM2 management, though further research is needed to optimize their use.