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Segaloff, R.E., Falk, J.D., House, J.M., Shoham, S., Mou, H., Jansen, E.A. and Isern, S. (2018) Obesity Promotes Severe Influenza A Virus Pathogenesis and Impairs the Antiviral Response. mBio Journal, 9, e00991-18.

has been cited by the following article:

• TITLE: Obesity and Pregnancy as Risk Factors for Influenza and Pneumonia

  AUTHORS: Padma Jyesta, Terry Oroszi

  KEYWORDS: Pregnancy, Obesity, Influenza, Pneumonia, Risk Factors, Antiviral, Vaccines

  JOURNAL NAME: Health, Vol.16 No.12, December 30, 2024

  ABSTRACT: Pregnancy and obesity have been identified as risk factors for severe influenza and pneumonia. These populations experience higher rates of respiratory complications, including pulmonary distress, hospitalization, and mortality. While the exact mechanisms for this increased susceptibility remain unclear, evidence suggests that the altered immune response in pregnant and obese individuals may play a significant role. This review aims to provide an overview of the impact of obesity and pregnancy on influenza and pneumonia, examining the risk factors, causes, management strategies, and the efficacy of antiviral treatments. Additionally, we explore the potential immunological processes contributing to the severity of these infections in these high-risk groups.