TITLE:
A Rare Case of Myoepithelial Carcinoma Associated with Recurrent Parotid Cancer Involving the Epiglottis: A Case Report and Comprehensive Literature Review
AUTHORS:
Imadoudini Hassimi Safia, Jie Jiang, Ulrich Parfait Ngom, Ping Wu, Yaoyun Tang
KEYWORDS:
Myoepithelial Carcinoma, Recurrent Parotid Cancer, Epiglottis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.13 No.12,
December
10,
2024
ABSTRACT: Background: Myoepithelial carcinoma is a rare form of parotid gland cancer characterized by its specific histopathological features involving malignant epithelial and myoepithelial cells. The occurrence of myoepithelial carcinoma after recurrent parotid gland cancer is particularly rare. Methods: This study describes a patient with myoepithelial carcinoma associated with recurrent parotid gland cancer involving the epiglottis. It includes presentation, recurrence, diagnosis, surgery, and follow-up. A search of PubMed, Enhances, and UK Biobank yielded data on pathologic features and treatment approaches for myoepithelial carcinoma outcomes: The patient originally diagnosed with parotid carcinoma underwent parotidectomy. Recurrence revealed myoepithelial carcinoma, squamous cell carcinoma and spindle cell components. Total parotidectomy followed by partial laryngectomy, reconstruction of laryngeal function, tracheotomy, adjuvant radiotherapy and chemotherapy. The patient was followed up with no evidence of disease. Conclusions: This case is an example of a rare local recurrence in the form of myoepithelial carcinoma after an initial diagnosis of parotid gland cancer. Surgical resection and chemoradiotherapy show promising results in the treatment of this difficult disease.