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S. M. Grundy, J. I. Cleeman, C. N. Merz, H. B. Brewer Jr., L. T. Clark, D. B. Hunninghake, R. C. Pasternak, S. C. Smith Jr. and N. J. Stone, “Coordinating Committee of the National Cholesterol Education Program, Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines,” Journal of the American College of Cardiology, Vol. 44, No. 3, 2004, pp. 720-32. doi:10.1016/j.jacc.2004.07.001
has been cited by the following article:
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TITLE:
Rosuvastatin Reduces Plasma Small Dense Ldl-Cholesterol Predominantly in Non-Diabetic Hypercholesterolemic Patients
AUTHORS:
Gen Yoshino, Saburo Nakano, Tomoko Matsumoto, Eiichi Murakami, Toshisuke Morita, Koji Kuboki
KEYWORDS:
Rosuvastatin; Small Dense LDL-Cholesterol (sdLDL); Large Buoyant LDL-C (lbLDL-C); Apolipoprotein (apo) B; Small Dense LDL-Cholesterol (sdLDL)/Large Buoyant LDL-C (lbLDL-C) Ratio
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.3 No.1,
January
12,
2012
ABSTRACT: Aims: Small dense LDL (sdLDL) cholesterol is considered a cardiovascular risk. Our purpose in this study was to evaluate the efficacy of rosuvastatin in reducing sdLDL and large buoyant LDL (lbLDL-C) in hypercholesterolemia. Methods: Fifty-six patients with a mean baseline LDL-cholesterol (LDL-C) concentration of 173.9 ± 40.5 mg/dL were treated with rosuvastatin 2.5 mg/day for 12 weeks. LDL-C, sdLDL-C, and apolipoprotein (apo) B were assessed and l lbLDL-C was calculated (LDL-C minus sdLDL-C). Results: After 12-week treatment with rosuvastatin 2.5mg, sdLDL-C and lbLDL-C were significantly reduced from 62.1 ± 23.8 mg/dL to 34.0 ± 13.4 mg/dL, p