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Khan, S., Tøndervik, A., Sletta, H., Klinkenberg, G., Emanuel, C., Onsøyen, E., et al. (2012) Overcoming Drug Resistance with Alginate Oligosaccharides Able to Potentiate the Action of Selected Antibiotics. Antimicrobial Agents and Chemotherapy, 56, 5134-5141.
https://doi.org/10.1128/aac.00525-12
has been cited by the following article:
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TITLE:
Preparative Fractionation of Feruloyl Oligosaccharides Produced by Combinatorial Enzyme Digestion of Arabinoxylan
AUTHORS:
Dominic W. S. Wong, Sarah Batt, William John Orts
KEYWORDS:
Format, Wheat Insoluble Arabinoxylan, Feruloyl Oligosaccharide, Combinatorial Enzyme Digestion
JOURNAL NAME:
Advances in Enzyme Research,
Vol.12 No.3,
September
30,
2024
ABSTRACT: Pretreated wheat insoluble arabinoxylan was converted to oligosaccharides of structural variants using combinatorial enzyme approach. The digestive products were separated by preparative scale chromatographic Amberlite XAD-2 column. Fractions containing feruloyl oligosaccharides (FOS) were isolated, pooled, freeze-dried, and demonstrated to possess antimicrobial activity. The FOS suppressed cell growth of the test organism ATCC 8739 E. coli with a MIC value of 0.028% (w/v, 35˚C, 24 hr). The antimicrobial action was observed exceeding 72 hr of culture incubation. The FOS product could be a useful source of prebiotics or preservatives. The present results further confirm the science and application of the concept of combinatorial enzyme technique.