TITLE:
Perinatal Morbidity and Mortality Associated with Maternal Diabetes in the Neonatology Department of the Issaka Gazoby Maternity Hospital, Niamey, Niger
AUTHORS:
Kamaye Moumouni, Samaila Aboubacar, Yahaya Mahamadou Moussa, Yahaya Haoua, Idrissa Massi Abdoulwahab, Garba Moumouni, Georges Thomas Ibrahim, Mamoudou Abdou Djafar, Barga Boubacar, Ali Hamani Amina, Gagara Mayaou Adama, Zeidou Abdoulaye, Soumana Alido, Mahamane Sani Mahamane Aminou
KEYWORDS:
Maternal Diabetes, Morbidity, Mortality, Perinatal, Niger
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.14 No.6,
November
4,
2024
ABSTRACT: Introduction: The association of diabetes and pregnancy is associated with a significantly higher risk of perinatal morbidity and mortality. The aim of this study was to investigate the perinatal morbidity and mortality associated with maternal diabetes at the Issaka Gazoby Maternity Hospital in Niamey. Methodology: This was a prospective case-control study conducted from April to September 2021 at the Issaka Gazoby Maternity Hospital in Niamey. “Cases” were neonates born to diabetic mothers, and “controls” were neonates born to non-diabetic mothers. The main dependent variable was the occurrence of perinatal complications. Analysis was performed using Epi info software 7.2.1. Pearson’s Chi2 test or Fisher’s exact test were used (p Results: Of the 2,225 admissions during the study period, 31 newborns were born to diabetic mothers (1.4%). Diabetic mothers were 2.8 times more likely to have a history of abortion (67.7% vs. 28.6%; OR = 2.82; p = 0.001). Similarly, a history of macrosomia was found in 29.0% of diabetic mothers versus 9.5% of controls (OR = 2.15; p = 0.01). Macrosomia was also more common in newborns of diabetic mothers (38.7% vs. 9.5%; OR = 2.63; p Conclusion: The risks of ante- and perinatal complications such as abortion, fetal macrosomia and stillbirth, as well as neonatal pathological events (macrosomia and malformations) were greater in newborns of diabetic mothers.