TITLE:
Acute Fatty Liver of Pregnancy—A Case Report in Grange University Hospital, Wales
AUTHORS:
Madinah Azeez, Alice Tayler, Simran Sharma
KEYWORDS:
Liver Disease, Coagulopathy, Obstetrics Medicine
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.14 No.10,
October
22,
2024
ABSTRACT: Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mortality. Patients typically present in the third trimester with non-specific symptoms, including nausea and vomiting, upper abdominal pain, malaise and anorexia. Initial diagnosis can be challenging due to the sometimes-insidious presentation, as well as the difficulty in distinguishing between AFLP and other conditions seen in pregnancy with overlapping features. We report a case study of a 32-year-old primigravida who presented with mild and non-specific symptoms, and examination findings leading to a timely diagnosis of AFLP were made. This case highlights the importance of early recognition, prompt intervention, and multidisciplinary management to achieve optimal maternal and fetal outcomes.