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Randerath, W., Verbraecken, J., Andreas, S., Arzt, M., Bloch, K.E., Brack, T., et al. (2016) Definition, Discrimination, Diagnosis and Treatment of Central Breathing Disturbances during Sleep. European Respiratory Journal, 49, 1600959.
https://doi.org/10.1183/13993003.00959-2016

has been cited by the following article:

• TITLE: Acquired Central Alveolar Hypoventilation as a Sequelae of Brainstem Tuberculoma

  AUTHORS: Boon Hau Ng, Hsueh Jing Low, Nik Nuratiqah Nik Abeed, Nor Safiqah Sharil, Rose Azzlinda Osman, Andrea Yu-Lin Ban

  KEYWORDS: Alveolar Hypoventilation, Tuberculoma, Mechanical Ventilation

  JOURNAL NAME: Open Access Library Journal, Vol.11 No.10, October 10, 2024

  ABSTRACT: Central alveolar hypoventilation (CAH) is a rare condition resulting from brainstem injury, characterised by a loss of automatic breathing. We present a case of a 16-year-old female initially diagnosed with a brainstem glioma based on magnetic resonance imaging brain. Following craniotomy and tumour debulking, she developed episodic apnoea during both wakefulness and sleep. Histopathological analysis of the brainstem specimen unexpectedly revealed a diagnosis of brainstem tuberculoma. Despite the initiation of anti-tuberculous therapy, the patient showed persistent CAH two weeks post-treatment. Management required tracheostomy and long-term pressure-control synchronised intermittent mandatory ventilation (PC-SIMV), which effectively stabilised her respiratory function.