TITLE:
Squamous Cell Carcinoma of the Middle Ear: Case Report and Literature Review
AUTHORS:
Mariam Harrak, Khouloud Ziani, Madiha Chelakhi, Othmane Saqri, Nabila Sellal, Mohamed El Hfid
KEYWORDS:
Chronic Suppurative Otitis, The Middle Ear, Squamous Cell Carcinoma, Surgery, Radiotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.15 No.9,
August
28,
2024
ABSTRACT: Malignant tumors originating from the middle ear are rare. The literature identifies chronic inflammation and Human Papillomavirus (HPV) infection as the most common risk factors. A CT scan to assess bony invasion and an MRI to evaluate soft tissue involvement, depth of invasion, and perineural invasion, followed by a biopsy, are indispensable for diagnosis and treatment. There is no standard treatment for squamous cell carcinoma of the middle ear, however, most reported cases are treated with surgical resection followed by postoperative radiotherapy. Given the challenges of achieving complete surgical excision, radiotherapy plays a crucial role in controlling middle ear cancers, as demonstrated in our case. We present a case of squamous cell carcinoma of the middle ear in a 63-year-old female with a history of chronic suppurative otitis media. The patient underwent a right subtotal petrosectomy without lymph node dissection followed by concurrent chemoradiotherapy. At the one-year follow visit, no recurrence or metastasis was detected.