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Liaqat, I., Riaz, N., Saleem, Q., Tahir, H.M., Arshad, M. and Arshad, N. (2018) Toxicological Evaluation of Essential Oils from Some Plants of Rutaceae Family. Evidence-Based Complementary and Alternative Medicine, 2018, Article ID: 4394687.
https://doi.org/10.1155/2018/4394687

has been cited by the following article:

• TITLE: Limonene’s Bacteriostatic Activity against Ralstonia solanacearum by Compromised Membrane Integrity: A Transcriptomic and Metabolomic Analysis

  AUTHORS: Ruya Zhang, Honghao Zhang, Linfeng Li, Yuchen Feng, Lin Yang, Jiaxin Liu, Senfeng Gao, Zihao Zhou, Yong Yang, Haibo Xiang, Mei Li, Yanyan Li

  KEYWORDS: Limonene, Transcriptome, Metabolome, Ralstonia solanacearum, Terpenoid Backbone Biosynthesis

  JOURNAL NAME: Journal of Agricultural Chemistry and Environment, Vol.13 No.3, August 23, 2024

  ABSTRACT: Ralstonia solanacearum, the causative agent of bacterial wilt, is a soil-borne pathogen that poses a widespread threat to plants in the Solanaceae family. To elucidate the mechanism by which limonene exerts its effects on R. solanacearum, we first assessed the impact of limonene on the physiological indicators of the pathogen and subsequently analyzed its transcriptome and metabolome. Our findings indicate that limonene has a potent inhibitory effect on R. solanacearum, and it also suppresses the formation of the bacterial community biofilm. Limonene primarily regulates the terpene biosynthesis pathway in R. solanacearum, thereby potentially affecting signal transduction in the pathogen and disrupting its normal growth and development. These results significantly enhance our understanding of limonene’s response to the induction of bacterial wilt and provide a reference for further prevention and control of R. solanacearum.