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Nikpouraghdam, M., Jalali, F.A., Alishiri, G., Heydari, S., Ebrahimnia, M., Samadinia, H., Sepandi, M., Jafari, N.J., Izadi, M., Qazvini, A., Dorostkar, R., Tat, M., Shahriary, A., Farnoosh, G;, Hosseini, Z., SR, Taghdir, M., Alimohamadi, Y., Abbaszadeh, S., Gouvarchin, G.H.E. and Bagheri, M., (2020) Epidemiological Characteristics of Coronavirus Disease 2019 (COVID-19) Patients in IRAN: A Single Center Study. Journal of Clinical Virology, 127, Article 104378.
https://doi.org/10.1016/j.jcv.2020.104378

has been cited by the following article:

• TITLE: Genomic Profile of SARS-COV-2 Associated with COVID-19 Outbreaks in N’Djamena, Chad

  AUTHORS: Mathieu Hota, Henry Yandai Fissou, Dezoumbe Koutaya, Djallaye Djimtoïbaye, Mahamat Moussa Ali

  KEYWORDS: COVID-19, SARS-CoV-2, Genomic Profile, Variant, Chad

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.15 No.7, July 31, 2024

  ABSTRACT: Background: SARS-CoV-2 has circulated worldwide with dramatic consequences. In Chad, we have no data reported of variants. The aim of this study was to identify the SARS-CoV-2 variants that circulated during the epidemic from 2020 to 2021. Methods: This is a cross-sectional, descriptive study carried out between 2020 and 2021. Samples from patients with suspected COVID-19 were tested in five laboratories in N’Djamena. One hundred quality samples of the positives were sequenced in Kinshasa using Oxford nanopore technologies minion and the Protocol Midnight SARS-CoV2. Data were processed using Excel version 16 software. Results: Of the 100 samples sequenced, 77 (77%) produced sequences, 23 (23%) did not. The genomic profiles were wild-type Wuhan and minor mutations (19A, 19B (A), 20A (B.1, B.2), 20B (AV.1), 20D (B.1.1.1 /C.36), 20C), variant of concern Alpha (20I), variant of concern Delta (21A/J), variant of interest Eta (21D), variant of concern Omicron (21K) and unclassified variant under surveillance (B.1.640). Of these variants, the maximums were detected in patients aged 26 - 35 with 30.26% and 25.26% in 36 - 45. However, 24.67% were in travelers and 75.32% in residents, 35.06% in those vaccinated against COVID-19 and 62.33% in non-vaccinates. The estimated case-fatality rate was 2.44% (107/4374). Conclusion: This work has provided preliminary data on COVID-19 and SARS-CoV-2 variants circulating during the 2020-2021 epidemics in Chad.