Article citationsMore>>
Hamdy, F., Donovan, J., Lane, J., Mason, M., Metcalfe, C., et al. (2016) 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer. The New England Journal of Medicine, 374, 1415-1424.
https://doi.org/10.1056/NEJMoa1606220
has been cited by the following article:
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TITLE:
Aminated Cyclopropylmethylphosphonates as Potent Prostate Cancer Inhibitors
AUTHORS:
Abed Al Aziz Al Quntar, Ibrahim Abasy
KEYWORDS:
Prostate Cancer, Cancer, Cyclopropylphophonates, Aminophosphonates, Cyclopropanes, Phosphonates, Alkynylphosphonates, Anti-Cancer, Prostate
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.12 No.7,
July
23,
2024
ABSTRACT: Inspired by the anti-pancreatic promising results of our novel aminated cyclopropylmethylphosphonate compounds, an in vitro anti-prostate cancer activity exploration of these compounds was carried out on human prostate cancer cell line PC-3, and showed potent inhibiting activity at low micromolar concentrations (with an IC50 of approximately 45 μM).