Article citationsMore>>
Gourlay, M.L., Fine, J.P., Preisser, J.S., May, R.C., Li, C., Lui, L.Y., Ransohoff, D.F., Cauley, J.A., Ensrud, K.E. and Study of Osteoporotic Fractures Research Group (2012) Bone-Density Testing Interval and Transition to Osteoporosis in Older Women. The New England Journal of Medicine, 366, 225-233.
https://doi.org/10.1056/NEJMoa1107142
has been cited by the following article:
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TITLE:
CT Thresholds for Spinal Bone Mineral Attenuation to Prioritize Eligible Older Women for Osteoporosis Screening
AUTHORS:
Seo Yeon K. Orite, Bryn Higuchi, Hyo-Chun Yoon, Lana H. Gimber
KEYWORDS:
Osteoporosis, Bone Mineral Attenuation, CT Threshold
JOURNAL NAME:
Open Journal of Radiology,
Vol.14 No.2,
June
28,
2024
ABSTRACT: Introduction: Computed tomography (CT) measurements of bone mineral attenuation may be a useful means to identify older women who should be prioritized for bone mineral density screening. Methods: We compared bone mineral attenuation as measured in the L1 vertebra of CT studies to the results of dual-energy x-ray absorptiometry (DEXA) studies to determine what CT attenuation thresholds might yield a reasonable combination of sensitivity and specificity for the detection of osteoporosis. The study was limited to women between the ages of 65 and 75 years who had a DEXA study and a CT that included the L1 or adjacent vertebra performed within 3 years of the DEXA study. Results: There were 1226 women in this study, of whom 452 (38%) had osteoporosis based on a T-score ≤ −2.5 by DEXA. There were 830 CT studies performed with contrast and 396 studies which were performed without contrast. There was a statistically significant difference in the mean HU of those studies performed without contrast compared to those with contrast (unenhanced mean 103 HU versus 125 HU, p