TITLE:
Bacteriological Profile of Effusion Fluids Infections at Charles De Gaulle University Pediatric Hospital from 2017 to 2020
AUTHORS:
Kambiré Dinanibè, Ouédraogo Oumarou, Tiendrebéogo Salam, Tondé Issa, Tamboura Mamadou, Zida Sylvie, Kpoda Dissinviel, Sagna Tani, Compaoré T. Rebeca, Zouré Abdou-Azaque, Soubeiga R. Serge Théophile, Sawadogo Stanislas, Ilboudo Maïmouna, Rouamba Hortense, Ouédraogo Wenkouni Henri Gautier, Ouédraogo-Traoré Rasmata, Sanou Mahamoudou
KEYWORDS:
Bacteriological Profile, Effusion Fluid, Infections
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.14 No.2,
June
28,
2024
ABSTRACT: Introduction: Microbiology of effusion fluids in children in Burkina Faso is characterized by the scarcity of data. This work aimed to study the bacteriological and antibiotics susceptibility profile of bacteria involved in effusion fluid infections in paediatrics in order to improve the choice of probabilistic antibiotics therapy. Methods: A cross-sectional, descriptive study was used in children aged 0 to 15 years from 2017 to 2020 at the Charles De Gaulle Pediatric University Hospital Center (CHUP-CDG) in Ouagadougou. Classical bacteriology methods such as macroscopy, Gram staining, identification galleries and antibiotics susceptibility testing were used. Results: Of 231 samples, 64 bacteria were isolated. The most common bacterial strains of pleural fluid were Staphylococcus aureus (25%) and 40% for Enterobacteriaceae. Of the peritoneal fluid, 77% were Enterobacteriaceae with 57% Escherichia coli; and from joint fluid, 33% were S. aureus and 22% for P. aeruginosa. The overall susceptibility profile showed 29% extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL), 10% methicillin-resistant S. aureus (MRSA), and 8% carbapenemases. Conclusion: Bacteriological profile is characterized by ESBL-producing Enterobacteriaceae and MRSA. The most active antibiotics were macrolides, aminoglycosides, and cefoxitin (methicillin) for Gram-positive cocci, carbapenems, and aminoglycosides for Gram-negative bacilli. Then, the monitoring of antibiotics resistance must be permanent.