Article citationsMore>>

Sandoval, B.A., Clayman, P.D., Oblinsky, D.G., Oh, S., Nakano, Y., Bird, M., et al. (2020) Photoenzymatic Reductions Enabled by Direct Excitation of Flavin-Dependent “Ene”-Reductases. Journal of the American Chemical Society, 143, 1735-1739.
https://doi.org/10.1021/jacs.0c11494

has been cited by the following article:

• TITLE: Recent Advances in Photoenzymatic Catalysis

  AUTHORS: Caiyi Xiang

  KEYWORDS: Photoenzymatic, Biocatalysis, Biocatalysts, ERED, “Ene”-Reductases, Nitroreductases, Flavin

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.14 No.2, June 20, 2024

  ABSTRACT: Photoenzymatic catalysis has become an emerging field in organic synthetic chemistry that provides eco-friendly alternatives to traditional methods. This comprehensive review examines the developing field of photoenzymatic catalysis, categorized by reaction types and focusing on its application in organic synthesis. This article highlights recent advances in the use of photoenzymatic reactions in carbon-carbon cross-coupling, ketone and alkene reduction, hydroamination, and hydrosulfonylation, mostly by flavin-dependent “ene”-reductases and nitroreductases. In each case, we exemplified the substrate scope that produces products with high yield and enantioselectivity. Additionally, the emerging trends in developing new enzymatic variants and novel reaction pathways that broaden the scope and enhance yield of these reactions were discussed.