TITLE:
Transmission Dynamics and Optimal Control Strategies of a Hand-Foot-Mouth Disease Model with Treatment and Vaccination Interventions
AUTHORS:
Jianping Wang, Shenghua Zou, Zhicai Guo
KEYWORDS:
Hand-Foot-Mouth Disease, Optimal Control, Transmission Dynamic, Vaccination Interventions
JOURNAL NAME:
Journal of Applied Mathematics and Physics,
Vol.12 No.6,
June
11,
2024
ABSTRACT: In this article, the transmission dynamics of a Hand-Foot-Mouth disease model with treatment and vaccination interventions are studied. We calculated the basic reproduction number and proved the global stability of disease-free equilibrium when R0 R0 > 1. Meanwhile, we obtained the optimal control strategies minimizing the cost of intervention and minimizing the infected person. We also give some numerical simulations to verify our theoretical results.