TITLE:
Bullous Pemphigoid Induced by Doxycycline: Case Report and Literature Review
AUTHORS:
Mishal Al Mebayadh, Rahaf Aldawish, Sohail A. Butt, Abdulrahman Saad Aljahhan
KEYWORDS:
Bullous Pemphigoid, Doxycycline, Drug-Associated Bullous Pemphigoid
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.13 No.5,
May
28,
2024
ABSTRACT: Bullous pemphigoid (BP) is the most prevalent autoimmune sub-epidermal blistering disease that affects mainly the elderly and could lead to serious morbidity. It has numerous risk factors and triggers, including an aging population with several comorbidities and drug exposure. In the published paper, we reported a case about a 32 years old male patient with unknown medical conditions who presented with erythematous patches and plaques on the scalp, face, and trunk with scattered blisters two weeks after initiating doxycycline treatment for folliculitis. The exact pathogenesis of the drug-reaction in drug- associated bullous pemphigoid (DABP) remains controversial. In conclusion, it is crucial for clinicians to be aware of DABP when prescribing doxycycline. The purpose of this case report is to raise awareness of the possible association between bullous pemphigoid and doxycycline.