TITLE:
Fulminant Hepatitis Associated with Chronic Consumption of 3,4-Methylenedioxy-Methamphetamine; Case Report
AUTHORS:
Ulises Solis Gomez, Gustavo Adolfo Hernández Valdez, Juan Antonio Contreras Escamilla, Ivan Alejandro Medina Jimenez, Jorge Morales Rojas, Jocelyn Nataly Quintero Melendez, Marco Antonio González Villar
KEYWORDS:
Fulminant Hepatitis, Acute Liver Failure, Methamphetamine, Severe Acute Liver Failure in a User of Drugs of Abuse, Hepatology
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.14 No.5,
May
24,
2024
ABSTRACT: The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA), also called ecstasy, is a neurotoxin widely consumed among young people that has increased in recent years because it is a recreational drug, of which immediate effects are known such as a greater sensation of well-being, extroversion, increased sensory perception. However, its long-term effects have been described very little in the medical literature, including damage to the heart, central nervous system, kidney, etc. One of its little-known effects is hepatotoxicity, of which few cases are known associated with fulminant hepatitis, which is a rapidly deteriorating condition that is generally associated with a syndrome of multiple organ dysfunction and death. Therefore, it is very important to know this type of damage in the short and long term. The following case is of a 39-year-old man who came to our service due to jaundice syndrome and the only history of MDMA consumption, who as the days went by met the criteria for fulminant liver failure, with damage to multiple organs (organ dysfunction syndrome).