TITLE:
Research Progress in Targeted Therapy for Esophageal Cancer
AUTHORS:
Jinming Hu, Yanhua Xu
KEYWORDS:
Immunotherapy, Targeted Therapy, Epidermal Growth Factor Receptor, Vascular Endothelial Growth Factor
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.12 No.5,
May
16,
2024
ABSTRACT: Esophageal cancer (EC) is a prevalent malignant tumor that affects the digestive system and is often linked to a poor prognosis. The absence of effective early screening methods results in the diagnosis of esophageal cancer (EC) patients at advanced or metastatic stages. While historically considered incurable, ongoing advancements in medical research have led to the integration of various treatment modalities as primary approaches for managing advanced endometrial cancer. These modalities include surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy. Notably, the introduction of targeted therapy and immunotherapy has significantly enhanced the survival rates of individuals with EC. Immunotherapy has appeared as the predominant treatment for advanced esophageal cancer, while targeted therapy faces certain obstacles. Consequently, this review primarily focuses on the advancements in targeted therapy for esophageal cancer (EC), evaluating the effectiveness and safety of relevant medications, and aiming to provide guidance for the comprehensive management of EC based on current research findings.