TITLE:
Research Progress on Zinc Sulfide Quantum Dots in Tumor in Vivo Imaging
AUTHORS:
Han He, Shuhui Huang, Jinxiao Ma, Juanli Cui, Xusheng Zhang
KEYWORDS:
Zinc Sulfide Quantum Dots, Tumor Imaging, Multimodal Imaging, Biocompatibility
JOURNAL NAME:
Open Access Library Journal,
Vol.11 No.4,
April
30,
2024
ABSTRACT: This study elaborates on the application and unique contributions of zinc sulfide quantum dots (ZnS QDs) in tumor imaging, highlighting their significant potential in the field of nanomedicine, particularly in tumor imaging techniques. Zinc sulfide quantum dots are distinguished by their superior optical properties, chemical stability, and excellent biocompatibility. Our research focuses on the customization of ZnS QDs through integration with biocompatible compounds, and the use of covalent bonding and self-assembly techniques to incorporate fluorescent and bioactive groups. This significantly enhances imaging precision and efficiency for specific tumor markers. Furthermore, we explore zinc sulfide quantum dots with multimodal imaging capabilities, such as manganese-doped CdS quantum dots (Mn:CdS QDs). This novel discovery paves the way for precise tumor detection, localization, and treatment. Despite the promising applications of zinc sulfide quantum dots, challenges including toxicity, stability, and biocompatibility issues must be addressed in their clinical translation. Thus, this paper calls for future research to focus on developing safer and more efficient new fluorescent probes and to delve deeper into the stability and drug release characteristics of quantum dots to facilitate their use in clinical tumor diagnosis and treatment.