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Spargias, K., Alexopoulos, E., Kyrzopoulos, S., Iokovis, P., Greenwood, D.C., Manginas, A., Voudris, V., Pavlides, G., Buller, C.E., Kremastinos, D. and Cokkinos, D.V. (2004) Ascorbic Acid Prevents Contrast-Mediated Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Angiography or Intervention. Circulation, 110, 2837-2842.
https://doi.org/10.1161/01.CIR.0000146396.19081.73

has been cited by the following article:

• TITLE: A Systematic Review of Contrast-Induced Acute Kidney Injury

  AUTHORS: Xing Li, Qiong Liu

  KEYWORDS: CI-AKI, ROS, Preventive Strategies, Antioxidants

  JOURNAL NAME: Open Journal of Nephrology, Vol.14 No.2, April 30, 2024

  ABSTRACT: Background: Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of AKI in hospitalized patients. Contrast agents mainly cause acute kidney injury through hypoxic damage to renal parenchyma and toxic effects on renal capillaries and tubules. Patients with CI-AKI are more likely to experience adverse events, including longer hospital stay and costs, longer ICU stay, and higher mortality rates. This article elaborates on the definition, epidemiology, risk factors, pathogenesis, and prevention strategies of CI-AKI. Methods: We conducted an extensive literature search using contrast agents and AKI as keywords to identify relevant studies on CI-AKI. Conclusion: CI-AKI is a significant clinical challenge that requires a multifaceted approach to prevention and management. Understanding the risk factors, pathophysiology, and current best practices is essential for healthcare providers to optimize patient care and improve outcomes in those undergoing contrast-enhanced imaging procedures. Hydration therapy is currently the main prevention method, but antioxidants may also become a new strategy.