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Hunsu, V.O., Facey, C.O.B., Fields, J.Z. and Boman, B.M. (2021) Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies. International Journal of Molecular Sciences, 22, Article 7731.
https://doi.org/10.3390/ijms22147731

has been cited by the following article:

• TITLE: Synthesis and Physico-Chemical Characterizations of Novel Hydrazone Ligands and Their Metal Complexes against Hormone-Dependent and Independent Cancers

  AUTHORS: Sommai Patitungkho, Kingkaew Patitungkho

  KEYWORDS: Metal Complexes, Cancers, Antioxidant, Hydrazone, Retinoid Receptors

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.14 No.1, March 29, 2024

  ABSTRACT: This work deals with the synthesis and physicochemical characterizations of a new group of novel retinoidal ligands and their metal complexes. Their in vitro anti-proliferative activities have shown that ligand L1 is effective against human breast cancer BT-20 and MCF-7 cell lines. At the same time, compound L2 exerts its effect on human prostate cancer PC-3 and human breast cancer MDA-MB-231 and MCF-7 cell lines respectively. The retinoid ligands exert their pleiotropic action toward retinoic acid receptors (RARs) than their metal complexes but all compounds exhibit concentration-dependent.