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Kadela-Tomanek, M., Bebenek, E., Chrobak, E., Marciniec, K., Latocha, M., Kuśmierz, D., Jastrzebska, M. and Boryczka, S. (2019) Betulin-1,4-Quinone Hybrids: Synthesis, Anticancer Activity and Molecular Docking Study with NQO1 Enzyme. European Journal of Medicinal Chemistry, 177, 302-315.
https://doi.org/10.1016/j.ejmech.2019.05.063

has been cited by the following article:

• TITLE: Steroids, Tri- and Meroterpenoids with a Quinone Structure—A Review

  AUTHORS: Maryam S. M. Aghaei, Thies Thiemann

  KEYWORDS: Steroid, Secosteroid, Meroterpenoid, Triterpenoid, Quinone, Anti-Tumour Agent, Antibiotic, Natural Product

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.14 No.1, March 29, 2024

  ABSTRACT: Terpenoids with quinoid structures are found as natural products. This includes steroidal quinones, quinones with a secosteroid structure and meroterpenoid quinones. Importantly, catechol estrogens as endogenous metabolites of estradiol and estrone are precursors of reactive quinones and semiquinones, which are thought to contribute to estrogen-induced carcinogenesis. On the other hand, a number of quinones that include substituted naphthoquinones and anthraquinones are highly cytotoxic and have been used in cancer treatment. This makes the structures interesting synthetic targets. The following is a review of important natural and synthetic terpenoid and steroid quinone hybrids.