Article citationsMore>>
Ortega, H.E., Graupner, P.R., Asai, Y., Ten Dyke, K., Qiu, D., Shen, Y.Y., Rios, N., Arnold, A.E., Coley, P.D., Kursar, T.A., Gerwick, W.H. and Cubilla-Rios, L. (2013) Mycoleptodiscins A and B, Cytotoxic Alkaloids from the Endophytic Fungus Mycoleptodiscus Sp. F0194. Journal of Natural Products, 76, 741-744.
https://doi.org/10.1021/np300792t
has been cited by the following article:
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TITLE:
Steroids, Tri- and Meroterpenoids with a Quinone Structure—A Review
AUTHORS:
Maryam S. M. Aghaei, Thies Thiemann
KEYWORDS:
Steroid, Secosteroid, Meroterpenoid, Triterpenoid, Quinone, Anti-Tumour Agent, Antibiotic, Natural Product
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.14 No.1,
March
29,
2024
ABSTRACT: Terpenoids with quinoid structures are found as natural products. This includes steroidal quinones, quinones with a secosteroid structure and meroterpenoid quinones. Importantly, catechol estrogens as endogenous metabolites of estradiol and estrone are precursors of reactive quinones and semiquinones, which are thought to contribute to estrogen-induced carcinogenesis. On the other hand, a number of quinones that include substituted naphthoquinones and anthraquinones are highly cytotoxic and have been used in cancer treatment. This makes the structures interesting synthetic targets. The following is a review of important natural and synthetic terpenoid and steroid quinone hybrids.