Article citationsMore>>

Pereira, R.B., Andrade, P.B. and Valentão, P. (2016) Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus. Marine Drugs, 14, Article No. 39.
https://doi.org/10.3390/md14020039

has been cited by the following article:

• TITLE: Steroids, Tri- and Meroterpenoids with a Quinone Structure—A Review

  AUTHORS: Maryam S. M. Aghaei, Thies Thiemann

  KEYWORDS: Steroid, Secosteroid, Meroterpenoid, Triterpenoid, Quinone, Anti-Tumour Agent, Antibiotic, Natural Product

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.14 No.1, March 29, 2024

  ABSTRACT: Terpenoids with quinoid structures are found as natural products. This includes steroidal quinones, quinones with a secosteroid structure and meroterpenoid quinones. Importantly, catechol estrogens as endogenous metabolites of estradiol and estrone are precursors of reactive quinones and semiquinones, which are thought to contribute to estrogen-induced carcinogenesis. On the other hand, a number of quinones that include substituted naphthoquinones and anthraquinones are highly cytotoxic and have been used in cancer treatment. This makes the structures interesting synthetic targets. The following is a review of important natural and synthetic terpenoid and steroid quinone hybrids.