TITLE:
Eyelid Kaposi Sarcoma in HIV-Negative Patient
AUTHORS:
Malalaniaina Andrianarison, Malala Razakanaivo, Rindra Rafanomezantsoa, Mendrika Fifaliana Rakotoarisaona, Odilon Laza, Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Léa Raobela, Lala Soavina Ramarozatovo, Fahafahantsoa Rapelanoro Rabenja
KEYWORDS:
Eyelid, HHV-8, Interferon, Kaposi Sarcoma
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.15 No.3,
March
25,
2024
ABSTRACT: Introduction: Kaposi sarcoma disease is a proliferative and multifocal disorder with
dual components, vascular and fibroblastic cellular, cutaneous and visceral
expression. Kaposi Sarcoma can affect the ocular surface and adnexa and can
masquerade as other entities, delaying prompt diagnosis can lead to diagnostic
wandering delaying treatment. Our aim is to describe a case of KS of the eyelid
in an HIV seronegative patient. Case Presentation: A seventy-year-old man developed a bilateral growing
tumoral reddish purple vascular mass on both the lower and upper eyelid
involving rapidly for 6 months. Both feet and the two shanks show the presence
of a brown-violet tumor-shaped formation. The patient was negative for HIV.
Histology examination showed a nodular tumor-like mass with a fibro hemangioma-epitheliomatous.
Polymerase chain reaction was positive for human herpes virus 8. Initial
chemotherapy followed by surgery was proposed
to the patient. Unfortunately, the patient rejected treatment and was lost to
follow-up. Conclusion: This case reports the difficulty of managing KS in
developing countries.