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Pinto, M., Sampaio, A., Gonçalves, R., Veiga, C., Rocha, L., Costa, D., Lopes, L., Ferreira, R., Valim, P., Chaveiro, K., Sathler, E., Vieira, R. and Bernardes, I. (2017) Study of the Effects of Photodynamic Therapy (PDT) on Scar-Induced Skin Wounds in Wistar Rats: The New Clinical Perspective for Ulcers. Modern Research in Inflammation, 6, 1-8.
https://doi.org/10.4236/mri.2017.61001

has been cited by the following article:

• TITLE: Treatment of Vulvovaginal Candidiasis with A Strategy Based on Phototherapy (M.A.C.® Scar Acceleration Method)

  AUTHORS: Marcus Vinicius de Mello Pinto, Karin Yuri Fernández Iturra, Aline Ronis Sampaio, María Elena Silva Álvarez, Esteban Fortuny

  KEYWORDS: Treatment of vulvovaginal Candidiasis, Candidiasis, Candida, M.A.C., MAC®

  JOURNAL NAME: Modern Research in Inflammation, Vol.13 No.1, February 29, 2024

  ABSTRACT: Candidiasis, also known as candidiasis vulvovaginitis, is an infection caused by different types of Candida fungi, the most frequent being Candida albicans. The present study reports an effective strategy, which opens new avenues for the treatment of this public health problem. The MAC® Methodology, conventional laser light-emitting (LLLT)/LED) methods are based on the biphasic response demonstrated many times in LLLT research and as with other forms of drugs, a “drug” (irradiation parameters) and a “dose” (irradiation times) and the “Arndt-Schulz Law” is often cited as a suitable model to describe the dose-dependent effects of LLLT. This method uses photopharmaceuticals, cell markers and the use of correct parameters for each case to induce the acceleration of tissue repair. The present study shows a case of a 32-year-old patient diagnosed with recurrent candidiasis 4 years ago. Eighteen sessions were performed (every other day) using a photoactivated component (Methylene blue 1% + Clotrimazole 1%) and LED phototherapy (red, blue and violet) with emission times of 60 - 260 seconds for each applicator, according to the dose recommendations of the scar acceleration method (MAC®). At the sixth treatment session there was a noticeable decrease in the itching sensation reported by the patient. In session 11 she reported feeling a great improvement, indicating that she no longer felt itching in any area after 18 sessions. The present case demonstrates new methodologies to treat common problems in the population that have a positive impact on the quality of life. This methodology has a promising future because it is non-invasive and requires a great biological transformation for inflammatory, fungal and viral control.