TITLE:
Nephroblastoma in Adults about a Clinical Case
AUTHORS:
Tounkara Cheickna, Coulibaly Amara, Malle Oumar Amadou, Bréhima Bolo Coulibaly, Bagoyoko Kaloga Daye, Samake Hamidou, Berthe Honoré Jean-Baptiste Gabriel, Diakite Mamadou Lamine
KEYWORDS:
Nephroblastoma, Malignant Kidney Tumor, Treatment, Adult, Mali
JOURNAL NAME:
Surgical Science,
Vol.15 No.2,
February
29,
2024
ABSTRACT: Nephroblastoma is
the most common malignant renal tumor in children and is related to an abnormal
proliferation of cells resembling those of the embryonic kidney (metanephroma),
hence the terminology; embryonal tumor. These are tumors that remain and remain
unstudied in Mali because they are common in adults in our context. Its annual
incidence is estimated at approximately 1/10,000 births. Nephroblastoma is a
rare or even exceptional tumor in adults. The clinical manifestation was
a large swelling of the right hypochondrium; abdominal pain for a year;
unquantified fever, hypertension, initial hematuria associated with burning
during urination and anemia. The main clinical manifestation remained fever and
abdominal pain. This renal tumor posed a diagnostic problem which was
previously labeled as a mesenteric tumor in our general surgery department. The
diagnosis was made by imaging: CT and magnetic resonance imaging. The treatment
is multidisciplinary and combines chemotherapy, surgery with or without
radiotherapy. The prognosis is poor due to late diagnosis and less
effectiveness of chemotherapy compared to the child. Survival did not exceed a
year and a half because the renal tumor in our patient was surgically overcome.
We report a case of nephroblastoma in an 86-year-old patient with unfavorable
histology (hematogenous metastases), operated on in the general surgery
department and whose postoperative course was simple and who was referred to
oncology for treatment.