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Padet, L., St-Amour, I., Aubin, E., Proulx, D. P., Bazin, R. and Lemieux, R. (2009) Dose-dependent inhibition of BrdU detection in the cell proliferation ELISA by culture medium proteins. Journal of Immunoassay and Immunochemistry, 30, 348-357. doi:10.1080/15321810903084863

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• TITLE: Modulation of human B lymphocyte differentiation by therapeutic immunoglobulins: from protein to mRNA levels

  AUTHORS: Nathalie Dussault, Nellie Dumont, Sonia Néron

  KEYWORDS: Human B Lymphocytes; CD40-CD154; IVIg; Differentiation; Immunomodulation

  JOURNAL NAME: Open Journal of Immunology, Vol.1 No.3, December 31, 2011

  ABSTRACT: Several groups are investigating the mechanisms of action of therapeutic immunoglobulins (IVIg) in order to improve their use. In vitro models such as CD40-CD154 interaction are necessary to study the physiological response of human B lymphocytes to IVIg. Human B lymphocytes treated with IVIg triggers a rapid phospho-rylation (