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Giricz, O., Lauer-Fields, J.L. and Fields, G.B. (2008) The normalization of gene expression data in melanoma: investigating the use of glyceraldehyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for quantitative real-time PCR. Analytical Biochemistry, 380, 137-139. doi:10.1016/j.ab.2008.05.024

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• TITLE: Modulation of human B lymphocyte differentiation by therapeutic immunoglobulins: from protein to mRNA levels

  AUTHORS: Nathalie Dussault, Nellie Dumont, Sonia Néron

  KEYWORDS: Human B Lymphocytes; CD40-CD154; IVIg; Differentiation; Immunomodulation

  JOURNAL NAME: Open Journal of Immunology, Vol.1 No.3, December 31, 2011

  ABSTRACT: Several groups are investigating the mechanisms of action of therapeutic immunoglobulins (IVIg) in order to improve their use. In vitro models such as CD40-CD154 interaction are necessary to study the physiological response of human B lymphocytes to IVIg. Human B lymphocytes treated with IVIg triggers a rapid phospho-rylation (