TITLE:
A Rare Cause of Leukocoria in Children: Persistent Hyperplastic Primary Vitreous
AUTHORS:
Prudence Ada Assoumou, Davy Alex Mouinga Abayi, Yoan Mboussou, Annick Kougou Ntoutoume, Helene Nyinko Aboughe, Olive Matsanga, Tatiana Harly Mba Aki, Emmanuel Mve Mengome
KEYWORDS:
PHVP, Leukocoria, Amblyopia, Ocular Imaging, Childhood
JOURNAL NAME:
Open Journal of Ophthalmology,
Vol.14 No.1,
February
27,
2024
ABSTRACT: Introduction: Leukocoria, a whitish pupillary reflection, is a common warning sign of various
pediatric ocular pathologies, including Persistent hyperplastic primary vitreous
(PHVP). This case report describes the observation of a 3-year-old child with melanoderma,
presenting with a white spot in the left eye since birth. Observation: Uncorrected
distance visual acuity was 2/10 in the right eye and hand movements were perceived
at 2 meters in the left eye. Examination of the anterior segment in the left eye
revealed leukocoria and microphthalmia. The fundus examination was normal in the
right eye but revealed a white mass extending from the center of the optic disc
towards the temporal region in the left eye. Ocular imaging, including ocular ultrasound
and optical coherence tomography, confirmed the diagnosis of PHVP, illustrated by
a residual white mass at the center of the optic disc in the left eye. Conclusion: PHVP should be considered in the presence of leukocoria in a child, with urgent
exclusion of retinoblastoma. This observation underscores the importance of early
diagnosis for appropriate management.