TITLE:
Bacteriological Profile of Infections Encountered in a Pneumology Service in a Moderate-Income Country [Pneumology Department of CHU Cocody (Côte d’Ivoire)]
AUTHORS:
Brou Jean Marcel Ahui, Alitonde Eudoxie Djegbeton, Alima Kone, Marc-Olivier Koffi, Kouame Clarisse Elogne, Mobio Nancy Hermine, Benjamin Kouraogo, Erick Akouatia, Constante Virginie Brou-Gode, Kigninlman Horo, Boko Alexandre Kouassi, Ngoran Koffi
KEYWORDS:
Bacterial Pleural, Pneumonia, Nosocomial Infection Sub-Saharan Africa, Antibiotic Therapy
JOURNAL NAME:
Open Journal of Respiratory Diseases,
Vol.14 No.1,
February
21,
2024
ABSTRACT: Introduction: Infections represent a real public health problem aggravating the morbidity and mortality of hospitalized patients. Methods: This was a retrospective study with descriptive purposes over a period of
05 years, in the Pneumology
Department of the University Hospital of Cocody. Results: The average age in our population was 42 years. We
observed a male predo- minance of 64.5%, with a sex ratio of 1.8. Medical
history was dominated by HIV infection (23.5%), followed by
tuberculosis (15.6%). Concerning lifestyle, smoking was found in 38% of cases.
Symptoms progressed chronically in 80% of cases. An infectious syndrome was
found in 75% of cases. Microbial culture was positive in 42%
of cases. Pseudomonas aeruginosa and Klebsiella pneumoniae were
encountered in 26.4% of cases each, followed by Echerichia coli in 10.4%
of cases. Klebsiella pneumoniae in
the first three years topped the list, but gradually. Pseudomonas aeruginosa maintained its leadership over the last three years. Pseudomonas aeruginosa isolates expressed a resistance rate of 9.8% to ceftazidime and 8.1% to
imipenem; to aztreonam (36%), ticarcillin (33.3%) and levofloxacin. These strains were susceptible to fosfomycin (100%),
mero- penem (96.6%) and amikacin (96%). For isolated
strains of Entero- bacteria- ceae, resistance was observed about ticarcillin (83.3%)
and amoxicillin clavula- nic acid (71.2%). Streptococcaceae showed resistance to tetracycline (69.2%) and
erythromycin (50%). Over the years there has been an increase in re- sistance to
amoxicillin-clavulanic acid ceftriaxone. The death rate was 14%. Conclusion: The bacterial profile of infections is dominated by
germs respon- sible for nosocomial infection with significant
mortality.