TITLE:
Using Optical Tweezers to Study the Friction of the Red Blood Cells
AUTHORS:
Edoukoua Jean Michel Konin, Pavel Yale, Abadê Ange-Boris N’guessan, Kouassi Benoit Kouakou, Abaka Michel Kouacou, Eugene Megnassan
KEYWORDS:
Friction, Indentation, Optical Tweezers, Tribology, Red Blood Cells
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.15 No.2,
February
8,
2024
ABSTRACT: In the last two decades the study of red blood cell elasticity
using optical tweezers has known a rise appearing in the scientific research
with regard to the various works carried out. Despite the various work done, no
study has been done so far to study the influence of friction on the red blood
cell indentation response using optical tweezers. In this study, we have
developed a new approach to determine the coefficient of friction as well as
the frictional forces of the red blood cell. This approach therefore allowed us
to simultaneously carry out the indentation and traction test, which allowed us
to extract the interfacial properties of the microbead red blood cell couple,
among other things, the friction coefficient. This property would be extremely
important to investigate the survival and mechanical features of cells, which
will be of great physiological and pathological significance. But taking into
account the hypothesis of friction as defined by the isotropic Coulomb law. The
experiment performed for this purpose is the Brinell Hardness Test (DB).