TITLE:
Possible Uses for Silymarin in Human Health: Systematic Review
AUTHORS:
Gisele Mara Silva Gonçalves, Andre Bernardo de Camargo Eisingher
KEYWORDS:
Silymarin, Flavonoids, Phytotherapeutic Drugs
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.15 No.2,
February
8,
2024
ABSTRACT: Silymarin, from the fruit of Silybum marianum, is known for its
hepatoprotective action. The aim of this study was to review the mechanisms of
action of the silymarin phytocomplex to expand the possibilities for its
application in human health. The search for
published articles was carried out on the CAPES Journals Portal
platform, which covers worldwide scientific databases. Publications from 2010
to 2022 were included. Of the 311 articles retrieved, 21 were included. The
articles discuss the diversity of silymarin’s applications and the possibility of optimizing its
bioavailability using drug delivery systems. Silymarin shows promise in
numerous diseases, such as liver, kidney, cardiovascular, respiratory and others. Its antiviral action has been demonstrated
in studies and silymarin has the potential to be used as a complementary
therapy in the treatment of many diseases, with the expectation that, in the
future, it will be used in therapeutic protocols for exclusive use.